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Jianpeng Ma(02-25-05)
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(07-20-05) Feed forward or backward regulatory modes in biology
(07-20-05) Feed forward or backward regulatory modes in biology
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(07-20-05) Feed forward or backward regulatory modes in biology
Today Mee H. Choi from Caltech talked Activation of CaMKII and Calcineurin. The relationship between Ca2+, Calmodulin, CaMKII is a typical feed forward loop, self-augmenting. The relationship between Ca2+, (some protein), Calcineurin is probably a feed backward loop, self-inhibitory(she hasn't studied it).These two kinds of regulatory mechanisms are very popular in biology.
Question: How to predict these loops from microarry data?
Yu Huang 2006-03-25
Gene Regulatory Networks Special Feature (PNAS)