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Joel Bader Seminar Note

stat mech background

phagosome, L. Stuart, Nature(in press)

Conserved Readout by alpha-helix or beta-sheet (Transcription factor/protein recognition codes)
In the process of searching for binding site, a TF is doing some sort of random walk along the chromosome and binds to the region with the lowest energy cost.

side-chain (water molecule facilitate) vs DNA (major or minor groove)

capture-recapture model

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